#  COMS Policies 

 



**COMS is responsible for reviewing all research projects at Harvard and its Affiliated Institutions involving specific materials, COMS-Regulated Materials (“**[CRM](/file_url/254)**”), as defined in the Policy Introduction. For research that falls under the purview of the NIH Guidelines, COMS reviews all projects conducted at or sponsored by COMS.**

Policies guiding all COMS regulated projects:

- [Memorandum Of Understanding](/file_url/224) (MOU)
- [COMS Introduction Policy](/sites/g/files/omnuum5351/files/2026-06/COMS%20Introduction%20Policy_0.pdf "COMS Introduction Policy")
- [COMS Policy on Recommended Containment Levels for Adenoviral Vectors in Laboratory Rats, Laboratory Mice and Laboratory Rabbits](/file_url/226)
- [COMS Policy on Recommended Containment Levels for use of Retroviral Vectors in Laboratory Rats, Laboratory Mice and Laboratory Rabbits](/file_url/227)
- [Biosafety Level 2+ Policy](/file_url/229)
- [Clinical Trials Policy](/file_url/230)
- [COMS Incident Reporting Policy](/sites/g/files/omnuum5351/files/2026-04/COMS%20Incident%20Reporting%20Policy%203-27-2026_2.pdf "COMS Incident Report Policy")
- [COMS Inspection Policy](/sites/g/files/omnuum5351/files/2026-06/COMS%20Inspection%20Policy.pdf "COMS Inspection Policy")
- [Lentiviral Vector Policy](/sites/g/files/omnuum5351/files/2025-01/Lentiviral%20Vector%20Policy%20Approved%202021.pdf "Lentiviral Vector Policy")
- [Liquid Waste Policy](/file_url/235)
- [Minutes Policy](/sites/g/files/omnuum5351/files/2025-05/Policy%20on%20Minutes%20of%20IBC%20Meeting%20Approved%20May%202%202025_0.pdf "Policy on Minutes of IBC Meeting")
- [Minutes Redaction Policy](/sites/g/files/omnuum5351/files/2025-05/Redaction%20of%20Minutes%20Policy%20Approved%20May%202%202025_0.pdf "Policy on Redacting Minutes of IBC Meeting ")
- [Protocol Review Policy](/sites/g/files/omnuum5351/files/2025-03/COMS%20Protocol%20Review%20Policy%20March%202025%20Final.pdf "COMS Protocol Review Policy")
- [Sharps Policy](/file_url/240)
- [Solid Waste Policy](/file_url/241)
- [COMS Training Policy](/sites/g/files/omnuum5351/files/2026-04/COMS%20Training%20Policy%203-27-2026.pdf "COMS Training Policy")
- [Validation and Use of Attenuated Organisms Policy](/file_url/243)

**Appendices**

1. [Biosafety Level 1 Practices](/file_url/244)
2. [Biosafety Level 2 Practices](/sites/g/files/omnuum5351/files/2025-08/BL2%20Appendix%207-25-2025.pdf "Biosafety Level 2 Appendix ")
3. [Biosafety Level 2+ Practices](/file_url/247)
4. [Biosafety Level 2 Additional Stipulations ](/file_url/248)